In a stunning recovery, Brad Green returns to the line-up after missing only four weeks with a broken jaw. Green broke his jaw during the first quarter of Melbourne's victory over Richmond in Round Four.
Defenders Jared Rivers and James Frawley also return after missing last week through injury. Rivers has overcome an ankle sprain while Frawley has recovered from a hip flexor injury.
Ruckman Mark Jamar has been named on the extended interchange after impressing with successful a returned to football for the Casey Scorpions last week. Jamie Bennell has also been named in the initial squad and is a chance to return after being rested last week.
Lynden Dunn and Shane Valenti have both been omitted. The final team of 22 will be announced at 5:00pm on Friday afternoon.
The last time the two sides met was at the MCG in Round 9 of last year, with Hawthorn 14.13.97 defeating Melbourne 12.6.78 in front of a crowd of 41,341.
Melbourne Squad
Backs: M.Whelan, M.Warnock, J.Rivers
In: Rivers, Frawley, Green, Bennell, Jamar